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Somatic Hypermutation Shapes the Antibody Repertoire of Memory B Cells in Humans

High-affinity antibodies produced by memory B cells differ from antibodies produced in naive B cells in two respects. First, many of these antibodies show somatic hypermutation, and second, the repertoire of antibodies expressed in memory responses is highly selected. To determine whether somatic hy...

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Detalles Bibliográficos
Autores principales: Meffre, Eric, Catalan, Nadia, Seltz, Françoise, Fischer, Alain, Nussenzweig, Michel C., Durandy, Anne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193472/
https://www.ncbi.nlm.nih.gov/pubmed/11489956

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