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Somatic Hypermutation Shapes the Antibody Repertoire of Memory B Cells in Humans
High-affinity antibodies produced by memory B cells differ from antibodies produced in naive B cells in two respects. First, many of these antibodies show somatic hypermutation, and second, the repertoire of antibodies expressed in memory responses is highly selected. To determine whether somatic hy...
Autores principales: | Meffre, Eric, Catalan, Nadia, Seltz, Françoise, Fischer, Alain, Nussenzweig, Michel C., Durandy, Anne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193472/ https://www.ncbi.nlm.nih.gov/pubmed/11489956 |
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