Point Mutation in Essential Genes with Loss or Mutation of the Second Allele: Relevance to the Retention of Tumor-Specific Antigens

Antigens that are tumor specific yet retained by tumor cells despite tumor progression offer stable and specific targets for immunologic and possibly other therapeutic interventions. Therefore, we have studied two CD4(+) T cell–recognized tumor-specific antigens that were retained during evolution o...

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Detalles Bibliográficos
Autores principales: Beck-Engeser, Gabriele B., Monach, Paul A., Mumberg, Dominik, Yang, Farley, Wanderling, Sherry, Schreiber, Karin, Espinosa, Rafael, Le Beau, Michelle M., Meredith, Stephen C., Schreiber, Hans
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193475/
https://www.ncbi.nlm.nih.gov/pubmed/11489948

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