Requirement for Transforming Growth Factor β1 in Controlling T Cell Apoptosis

Transforming growth factor (TGF)-β1, a potent immunoregulatory molecule, was found to control the life and death decisions of T lymphocytes. Both thymic and peripheral T cell apoptosis was increased in mice lacking TGF-β1 (TGF-β1(−/−)) compared with wild-type littermates. Engagement of the T cell re...

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Detalles Bibliográficos
Autores principales: Chen, WanJun, Jin, Wenwen, Tian, Hongsheng, Sicurello, Paula, Frank, Mark, Orenstein, Jan M., Wahl, Sharon M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193497/
https://www.ncbi.nlm.nih.gov/pubmed/11514601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193497/
https://www.ncbi.nlm.nih.gov/pubmed/11514601

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