Selective Abrogation of Major Histocompatibility Complex Class II Expression on Extrahematopoietic Cells in Mice Lacking Promoter IV of the Class II Transactivator Gene

MHC class II (MHCII) molecules play a pivotal role in the induction and regulation of immune responses. The transcriptional coactivator class II transactivator (CIITA) controls MHCII expression. The CIITA gene is regulated by three independent promoters (pI, pIII, pIV). We have generated pIV knockou...

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Detalles Bibliográficos
Autores principales: Waldburger, Jean-Marc, Suter, Tobias, Fontana, Adriano, Acha-Orbea, Hans, Reith, Walter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193506/
https://www.ncbi.nlm.nih.gov/pubmed/11514597

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