Deamidation of Asparagine in a Major Histocompatibility Complex–Bound Peptide Affects T Cell Recognition but Does Not Explain Type B Reactivity

We have analyzed a panel of T cell hybridomas specific for the chemically dominant epitope of hen egg-white lysozyme 48–61 which has asparagine 59 as an important T cell receptor contact residue. A number of T cells recognize 48–61 with asparagine at position 59, but not the aspartic acid or isoaspa...

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Detalles Bibliográficos
Autores principales: Cirrito, Thomas P., Pu, Zheng, Deck, M. Brian, Unanue, Emil R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193507/
https://www.ncbi.nlm.nih.gov/pubmed/11602644

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