Legionella pneumophila Is Internalized by a Macropinocytotic Uptake Pathway Controlled by the Dot/Icm System and the Mouse Lgn1 Locus(✪)

The products of the Legionella pneumophila dot/icm genes enable the bacterium to replicate within a macrophage vacuole. This study demonstrates that the Dot/Icm machinery promotes macropinocytotic uptake of L. pneumophila into mouse macrophages. In mouse strains harboring a permissive Lgn1 allele, L...

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Detalles Bibliográficos
Autores principales: Watarai, Masahisa, Derre, Isabelle, Kirby, James, Growney, Joseph D., Dietrich, William F., Isberg, Ralph R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193510/
https://www.ncbi.nlm.nih.gov/pubmed/11602638

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