Cd8(−) T Cell Transfectants That Express a High Affinity T Cell Receptor Exhibit Enhanced Peptide-Dependent Activation

T cells are activated by binding of the T cell receptor (TCR) to a peptide-major histocompatibility complex (MHC) complex (pMHC) expressed on the surface of antigen presenting cells. Various models have predicted that activation is limited to a narrow window of affinities (or dissociation rates) for...

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Detalles Bibliográficos
Autores principales: Holler, Phillip D., Lim, Alice R., Cho, Bryan K., Rund, Laurie A., Kranz, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193521/
https://www.ncbi.nlm.nih.gov/pubmed/11602635

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