Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

The most common human leukemia is B cell chronic lymphocytic leukemia (CLL), a malignancy of mature B cells with a characteristic clinical presentation but a variable clinical course. The rearranged immunoglobulin (Ig) genes of CLL cells may be either germ-line in sequence or somatically mutated. La...

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Detalles Bibliográficos
Autores principales: Rosenwald, Andreas, Alizadeh, Ash A., Widhopf, George, Simon, Richard, Davis, R. Eric, Yu, Xin, Yang, Liming, Pickeral, Oxana K., Rassenti, Laura Z., Powell, John, Botstein, David, Byrd, John C., Grever, Michael R., Cheson, Bruce D., Chiorazzi, Nicholas, Wilson, Wyndham H., Kipps, Thomas J., Brown, Patrick O., Staudt, Louis M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193523/
https://www.ncbi.nlm.nih.gov/pubmed/11733578

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