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Involvement of the TCR Cβ FG Loop in Thymic Selection and T Cell Function

The asymmetric disposition of T cell receptor (TCR) Cβ and Cα ectodomains creates a cavity with a side-wall formed by the rigid Cβ FG loop. To investigate the significance of this conserved structure, we generated loop deletion (βΔFG) and βwt transgenic (tg) mice using the TCR β subunit of the N15 C...

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Detalles Bibliográficos
Autores principales:	Sasada, Tetsuro, Touma, Maki, Chang, Hsiu-Ching, Clayton, Linda K., Wang, Jia-huai, Reinherz, Ellis L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193539/ https://www.ncbi.nlm.nih.gov/pubmed/12045240 http://dx.doi.org/10.1084/jem.20020119

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