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Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets

Dendritic cells (DCs) play a crucial role in the immune responses against infections by sensing microbial invasion through toll-like receptors (TLRs). In humans, two distinct DC subsets, CD11c(−) plasmacytoid DCs (PDCs) and CD11c(+) myeloid DCs (MDCs), have been identified and can respond to differe...

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Detalles Bibliográficos
Autores principales: Ito, Tomoki, Amakawa, Ryuichi, Kaisho, Tsuneyasu, Hemmi, Hiroaki, Tajima, Kenichirou, Uehira, Kazutaka, Ozaki, Yoshio, Tomizawa, Hideyuki, Akira, Shizuo, Fukuhara, Shirou
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193542/
https://www.ncbi.nlm.nih.gov/pubmed/12045249
http://dx.doi.org/10.1084/jem.20020207

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