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Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets
Dendritic cells (DCs) play a crucial role in the immune responses against infections by sensing microbial invasion through toll-like receptors (TLRs). In humans, two distinct DC subsets, CD11c(−) plasmacytoid DCs (PDCs) and CD11c(+) myeloid DCs (MDCs), have been identified and can respond to differe...
Autores principales: | Ito, Tomoki, Amakawa, Ryuichi, Kaisho, Tsuneyasu, Hemmi, Hiroaki, Tajima, Kenichirou, Uehira, Kazutaka, Ozaki, Yoshio, Tomizawa, Hideyuki, Akira, Shizuo, Fukuhara, Shirou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193542/ https://www.ncbi.nlm.nih.gov/pubmed/12045249 http://dx.doi.org/10.1084/jem.20020207 |
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