Cargando…
Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8(+) T Cells
Transgenic (TG) mice expressing a high copy number of interleukin (IL)-7 cDNA under the control of the major histocomaptability complex (MHC) class II promoter display a 10–20-fold increase in total T cell numbers. Here, we show that the increase in T cell numbers in IL-7 TG mice is most apparent at...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193553/ https://www.ncbi.nlm.nih.gov/pubmed/12070281 http://dx.doi.org/10.1084/jem.20020067 |