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Constitutive Endocytosis and Degradation of the Pre-T Cell Receptor
The pre-T cell receptor (TCR) signals constitutively in the absence of putative ligands on thymic stroma and signal transduction correlates with translocation of the pre-TCR into glycolipid-enriched microdomains (rafts) in the plasma membrane. Here, we show that the pre-TCR is constitutively routed...
Autores principales: | Panigada, Maddalena, Porcellini, Simona, Barbier, Eliane, Hoeflinger, Sonja, Cazenave, Pierre-André, Gu, Hua, Band, Hamid, von Boehmer, Harald, Grassi, Fabio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193560/ https://www.ncbi.nlm.nih.gov/pubmed/12070286 http://dx.doi.org/10.1084/jem.20020047 |
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