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Active Immunization Against the Vascular Endothelial Growth Factor Receptor flk1 Inhibits Tumor Angiogenesis and Metastasis

The vascular endothelial growth factor (VEGF) receptor fetal liver kinase 1 (flk1; VEGFR-2, KDR) is an endothelial cell–specific receptor tyrosine kinase that mediates physiological and pathological angiogenesis. We hypothesized that an active immunotherapy approach targeting flk1 may inhibit tumor...

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Detalles Bibliográficos
Autores principales:	Li, Yiwen, Wang, Mei-Nai, Li, Hongli, King, Karen D., Bassi, Rajiv, Sun, Haijun, Santiago, Angel, Hooper, Andrea T., Bohlen, Peter, Hicklin, Daniel J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193561/ https://www.ncbi.nlm.nih.gov/pubmed/12070285 http://dx.doi.org/10.1084/jem.20020072

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