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Matrix Metalloproteinases (MMPs) Regulate Fibrin-invasive Activity via MT1-MMP–dependent and –independent Processes
Cross-linked fibrin is deposited in tissues surrounding wounds, inflammatory sites, or tumors and serves not only as a supporting substratum for trafficking cells, but also as a structural barrier to invasion. While the plasminogen activator-plasminogen axis provides cells with a powerful fibrinolyt...
Autores principales: | Hotary, Kevin B., Yana, Ikuo, Sabeh, Farideh, Li, Xiao-Yan, Holmbeck, Kenn, Birkedal-Hansen, Henning, Allen, Edward D., Hiraoka, Nobuaki, Weiss, Stephen J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193588/ https://www.ncbi.nlm.nih.gov/pubmed/11828004 http://dx.doi.org/10.1084/jem.20010815 |
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