Complementary Dendritic Cell–activating Function of CD8(+) and CD4(+) T Cells: Helper Role of CD8(+) T Cells in the Development of T Helper Type 1 Responses

Dendritic cells (DCs) activated by CD40L-expressing CD4(+) T cells act as mediators of “T helper (Th)” signals for CD8(+) T lymphocytes, inducing their cytotoxic function and supporting their long-term activity. Here, we show that the optimal activation of DCs, their ability to produce high levels o...

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Detalles Bibliográficos
Autores principales: Mailliard, Robbie B., Egawa, Shinichi, Cai, Quan, Kalinska, Anna, Bykovskaya, Svetlana N., Lotze, Michael T., Kapsenberg, Martien L., Storkus, Walter J., Kalinski, Pawel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193623/
https://www.ncbi.nlm.nih.gov/pubmed/11854360
http://dx.doi.org/10.1084/jem.20011662

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