Cargando…
T Cell Receptor β Chain Lacking the Large Solvent-exposed Cβ FG Loop Supports Normal α/β T Cell Development and Function in Transgenic Mice
The striking and unique structural feature of the T cell receptor (TCR) β chain is the bulky solvent-exposed FG loop on the Cβ domain, the size of almost half an immunoglobulin domain. The location and size of this loop suggested immediately that it could be a crucial structural link between the inv...
Autores principales: | Degermann, Sylvie, Sollami, Giuseppina, Karjalainen, Klaus |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193633/ https://www.ncbi.nlm.nih.gov/pubmed/10330447 |
Ejemplares similares
-
Impaired Nk1.1 T Cell Development in Mice Transgenic for a T Cell Receptor β Chain Lacking the Large, Solvent-Exposed Cβ Fg Loop
por: Degermann, Sylvie, et al.
Publicado: (1999) -
Involvement of the TCR Cβ FG Loop in Thymic Selection and T Cell Function
por: Sasada, Tetsuro, et al.
Publicado: (2002) -
Signaling Efficiency of the T Cell Receptor Controlled by a Single Amino Acid in the β Chain Constant Region
por: Bäckström, B. Thomas, et al.
Publicado: (1997) -
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
por: Kim, Jungsu, et al.
Publicado: (2012) -
One of the CD3ε Subunits within a T Cell Receptor Complex Lies in Close Proximity to the Cβ FG Loop
por: Ghendler, Yoseph, et al.
Publicado: (1998)