Cargando…
Synaptotagmin II Negatively Regulates Ca(2+)-triggered Exocytosis of Lysosomes in Mast Cells
Synaptotagmins (Syts) I and II are believed to act as Ca(2+) sensors in the control of neurotransmission. Here we demonstrate that mast cells express Syt II in their lysosomal fraction. We further show that activation of mast cells by either aggregation of FcεRI or by Ca(2+) ionophores results in ex...
Autores principales: | Baram, Dana, Adachi, Roberto, Medalia, Ora, Tuvim, Michael, Dickey, Burton F., Mekori, Yoseph A., Sagi-Eisenberg, Ronit |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193646/ https://www.ncbi.nlm.nih.gov/pubmed/10330444 |
Ejemplares similares
-
Anaphylactic Degranulation of Mast Cells: Focus on Compound Exocytosis
por: Klein, Ofir, et al.
Publicado: (2019) -
Synaptotagmin VII Regulates Ca(2+)-Dependent Exocytosis of Lysosomes in Fibroblasts
por: Martinez, Iñigo, et al.
Publicado: (2000) -
Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis
por: Jaiswal, Jyoti K, et al.
Publicado: (2004) -
A molecular mechanism for calcium/synaptotagmin-triggered exocytosis
por: Kiessling, Volker, et al.
Publicado: (2018) -
Productive and Non-productive Pathways for Synaptotagmin 1 to Support Ca(2+)-Triggered Fast Exocytosis
por: Kim, Jaewook, et al.
Publicado: (2017)