HIV-1 Vpr Enhances Viral Burden by Facilitating Infection of Tissue Macrophages but Not Nondividing CD4(+) T Cells

Prior experiments in explants of human lymphoid tissue have demonstrated that human immunodeficiency virus type 1 (HIV-1) productively infects diverse cellular targets including T cells and tissue macrophages. We sought to determine the specific contribution of macrophages and T cells to the overall...

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Detalles Bibliográficos
Autores principales: Eckstein, Daniel A., Sherman, Michael P., Penn, Michael L., Chin, Peggy S., De Noronha, Carlos M.C., Greene, Warner C., Goldsmith, Mark A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193684/
https://www.ncbi.nlm.nih.gov/pubmed/11714748

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