Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System

The CDR3 regions of T cell receptor (TCR)-α and -β chains play central roles in the recognition of antigen (Ag)-MHC complex. TCR repertoire is created on the basis of Ag recognition specificity by CDR3s. To analyze the potential spectrum of TCR-α and -β to exhibit Ag specificity and generate TCR rep...

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Detalles Bibliográficos
Autores principales: Yokosuka, Tadashi, Takase, Kan, Suzuki, Misao, Nakagawa, Yohko, Taki, Shinsuke, Takahashi, Hidemi, Fujisawa, Takehiko, Arase, Hisashi, Saito, Takashi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193687/
https://www.ncbi.nlm.nih.gov/pubmed/11956290
http://dx.doi.org/10.1084/jem.20010809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193687/
https://www.ncbi.nlm.nih.gov/pubmed/11956290
http://dx.doi.org/10.1084/jem.20010809

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