Escaping High Viral Load Exhaustion: CD8 Cells with Altered Tetramer Binding in Chronic Hepatitis B Virus Infection

Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in the face of a high quantity of viral antigen....

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Detalles Bibliográficos
Autores principales: Reignat, Stephanie, Webster, George J.M., Brown, David, Ogg, Graham S., King, Abigail, Seneviratne, Suranjith L., Dusheiko, Geoff, Williams, Roger, Maini, Mala K., Bertoletti, Antonio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193712/
https://www.ncbi.nlm.nih.gov/pubmed/11994415
http://dx.doi.org/10.1084/jem.20011723

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