Cargando…

c-Jun NH(2)-Terminal Kinase (JNK)1 and JNK2 Signaling Pathways Have Divergent Roles in CD8(+) T Cell–mediated Antiviral Immunity

c-Jun NH(2)-terminal kinases (JNK) play important roles in T helper cell (Th) proliferation, differentiation, and maintenance of Th1/Th2 polarization. To determine whether JNKs are involved in antiviral T cell immunity, and whether JNK1 and JNK2 bear biological differences, we investigated the immun...

Descripción completa

Detalles Bibliográficos
Autores principales: Arbour, Nathalie, Naniche, Denise, Homann, Dirk, Davis, Roger J., Flavell, Richard A., Oldstone, Michael B.A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193720/
https://www.ncbi.nlm.nih.gov/pubmed/11927625
http://dx.doi.org/10.1084/jem.20011481