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B-1a B Cells that Link the Innate and Adaptive Immune Responses Are Lacking in the Absence of the Spleen

Splenectomized individuals are prone to overwhelming infections with encapsulated bacteria and splenectomy of mice increases susceptibility to streptococcal infections, yet the exact mechanism by which the spleen protects against such infections is unknown. Using congenitally asplenic mice as a mode...

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Detalles Bibliográficos
Autores principales:	Wardemann, Hedda, Boehm, Thomas, Dear, Neil, Carsetti, Rita
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193734/ https://www.ncbi.nlm.nih.gov/pubmed/11901202 http://dx.doi.org/10.1084/jem.20011140

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