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Modulation of LIGHT-HVEM Costimulation Prolongs Cardiac Allograft Survival

LIGHT (TNFSF14), a tumor necrosis factor superfamily member expressed by activated T cells, binds to herpes virus entry mediator (HVEM) which is constitutively expressed by T cells and costimulates T cell activation in a CD28-independent manner. Given interest in regulating the effector functions of...

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Detalles Bibliográficos
Autores principales: Ye, Qunrui, Fraser, Christopher C., Gao, Wei, Wang, Liqing, Busfield, Samantha J., Wang, Chichung, Qiu, Yubin, Coyle, Anthony J., Gutierrez-Ramos, Jose-Carlos, Hancock, Wayne W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193745/
https://www.ncbi.nlm.nih.gov/pubmed/11901205
http://dx.doi.org/10.1084/jem.20012088