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Modulation of LIGHT-HVEM Costimulation Prolongs Cardiac Allograft Survival
LIGHT (TNFSF14), a tumor necrosis factor superfamily member expressed by activated T cells, binds to herpes virus entry mediator (HVEM) which is constitutively expressed by T cells and costimulates T cell activation in a CD28-independent manner. Given interest in regulating the effector functions of...
Autores principales: | Ye, Qunrui, Fraser, Christopher C., Gao, Wei, Wang, Liqing, Busfield, Samantha J., Wang, Chichung, Qiu, Yubin, Coyle, Anthony J., Gutierrez-Ramos, Jose-Carlos, Hancock, Wayne W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193745/ https://www.ncbi.nlm.nih.gov/pubmed/11901205 http://dx.doi.org/10.1084/jem.20012088 |
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