Cathepsin L Regulates CD4(+) T Cell Selection Independently of Its Effect on Invariant Chain: A Role in the Generation of Positively Selecting Peptide Ligands

CD4(+) T cells are positively selected in the thymus on peptides presented in the context of major histocompatibility complex class II molecules expressed on cortical thymic epithelial cells. Molecules regulating this peptide presentation play a role in determining the outcome of positive selection....

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Detalles Bibliográficos
Autores principales: Honey, Karen, Nakagawa, Terry, Peters, Christoph, Rudensky, Alexander
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193748/
https://www.ncbi.nlm.nih.gov/pubmed/12021314
http://dx.doi.org/10.1084/jem.20011904

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