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Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

The constraint of fitting a diverse repertoire of antigen specificities in a limited total population of lymphocytes results in the frequency of naive cells specific for any given antigen (defined as the precursor frequency) being below the limit of detection by direct measurement. We have estimated...

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Detalles Bibliográficos
Autores principales:	Blattman, Joseph N., Antia, Rustom, Sourdive, David J.D., Wang, Xiaochi, Kaech, Susan M., Murali-Krishna, Kaja, Altman, John D., Ahmed, Rafi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193761/ https://www.ncbi.nlm.nih.gov/pubmed/11877489 http://dx.doi.org/10.1084/jem.20001021

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