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Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease

Celiac disease is caused by a selective lack of T cell tolerance for gluten. It is known that the enzyme tissue transglutaminase (tTG) is involved in the generation of T cell stimulatory gluten peptides through deamidation of glutamine, the most abundant amino acid in gluten. Only particular glutami...

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Detalles Bibliográficos
Autores principales:	Vader, L. Willemijn, de Ru, Arnoud, van der Wal, Yvonne, Kooy, Yvonne M.C., Benckhuijsen, Willemien, Mearin, M. Luisa, Drijfhout, Jan Wouter, van Veelen, Peter, Koning, Frits
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193762/ https://www.ncbi.nlm.nih.gov/pubmed/11877487 http://dx.doi.org/10.1084/jem.20012028

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