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Toll-like Receptor 4 Resides in the Golgi Apparatus and Colocalizes with Internalized Lipopolysaccharide in Intestinal Epithelial Cells

Toll-like receptor (TLR) 4 is mainly found on cells of the myelopoietic lineage. It recognizes lipopolysaccharide (LPS) and mediates cellular activation and production of proinflammatory cytokines. Less is known about the distribution and role of TLR4 in epithelial cells that are continuously expose...

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Detalles Bibliográficos
Autores principales: Hornef, Mathias W., Frisan, Teresa, Vandewalle, Alain, Normark, Staffan, Richter-Dahlfors, Agneta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193765/
https://www.ncbi.nlm.nih.gov/pubmed/11877479
http://dx.doi.org/10.1084/jem.20011788