Essential Immunoregulatory Role for BCAP in B Cell Development and Function

BCAP was recently cloned as a binding molecule to phosphoinositide 3-kinase (PI3K). To investigate the role of BCAP, mutant mice deficient in BCAP were generated. While BCAP-deficient mice are viable, they have decreased numbers of mature B cells and B1 B cell deficiency. The mice produce lower tite...

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Detalles Bibliográficos
Autores principales: Yamazaki, Tetsuo, Takeda, Kiyoshi, Gotoh, Kumiko, Takeshima, Hiroshi, Akira, Shizuo, Kurosaki, Tomohiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193770/
https://www.ncbi.nlm.nih.gov/pubmed/11877477
http://dx.doi.org/10.1084/jem.20011751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193770/
https://www.ncbi.nlm.nih.gov/pubmed/11877477
http://dx.doi.org/10.1084/jem.20011751

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