Critical Role of the Carboxyl Terminus of Proline-rich Tyrosine Kinase (Pyk2) in the Activation of Human Neutrophils by Tumor Necrosis Factor: Separation of Signals for the Respiratory Burst and Degranulation

Transduction of Tat-tagged fusion proteins confirmed a hypothesis based on pharmacologic inhibitors (Fuortes, M., M. Melchior, H. Han, G.J. Lyon, and C. Nathan. 1999. J. Clin. Invest. 104:327–335) that proline-rich tyrosine kinase (Pyk2) plays a critical role in the activation of adherent human neut...

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Detalles Bibliográficos
Autores principales: Han, Hyunsil, Fuortes, Michele, Nathan, Carl
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193795/
https://www.ncbi.nlm.nih.gov/pubmed/12515814
http://dx.doi.org/10.1084/jem.20021638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193795/
https://www.ncbi.nlm.nih.gov/pubmed/12515814
http://dx.doi.org/10.1084/jem.20021638

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