Cargando…
Enhanced B Cell Expansion, Survival, and Humoral Responses by Targeting Death Receptor 6
Targeted disruption of death receptor (DR)6 results in enhanced CD4(+) T cell expansion and T helper cell type 2 differentiation after stimulation. Similar to T cells, DR6 is expressed on resting B cells but is down-regulated upon activation. We examined DR6(−/−) B cell responses both in vitro and i...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193799/ https://www.ncbi.nlm.nih.gov/pubmed/12515813 http://dx.doi.org/10.1084/jem.20020617 |