Enhanced B Cell Expansion, Survival, and Humoral Responses by Targeting Death Receptor 6

Targeted disruption of death receptor (DR)6 results in enhanced CD4(+) T cell expansion and T helper cell type 2 differentiation after stimulation. Similar to T cells, DR6 is expressed on resting B cells but is down-regulated upon activation. We examined DR6(−/−) B cell responses both in vitro and i...

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Detalles Bibliográficos
Autores principales: Schmidt, Clint S., Liu, Jinqi, Zhang, Tonghai, Song, Ho Yeong, Sandusky, George, Mintze, Karen, Benschop, Robert J., Glasebrook, Andrew, Yang, Derek D., Na, Songqing
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193799/
https://www.ncbi.nlm.nih.gov/pubmed/12515813
http://dx.doi.org/10.1084/jem.20020617

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