Expression of ICOS In Vivo Defines CD4(+) Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10

The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the nature and function of ICOS-expressing T cells in vivo. We examined ICOS(+) T cells in the secondary lymphoid organs of nonmanipulated mice, i...

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Detalles Bibliográficos
Autores principales: Löhning, Max, Hutloff, Andreas, Kallinich, Tilmann, Mages, Hans Werner, Bonhagen, Kerstin, Radbruch, Andreas, Hamelmann, Eckard, Kroczek, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193816/
https://www.ncbi.nlm.nih.gov/pubmed/12538658
http://dx.doi.org/10.1084/jem.20020632

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