Cargando…

The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c

Caspase activation is a central event in numerous forms of apoptosis and results in the proteolytic degradation of multiple substrate proteins that contribute to the apoptotic phenotype. An important route to caspase activation proceeds via assembly of the “apoptosome” as a result of the cell stress...

Descripción completa

Detalles Bibliográficos
Autores principales: Murphy, Brona M., O'Neill, Amanda J., Adrain, Colin, Watson, R. William G., Martin, Seamus J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193828/
https://www.ncbi.nlm.nih.gov/pubmed/12615903
http://dx.doi.org/10.1084/jem.20021862