The Poxvirus Protein A52R Targets Toll-like Receptor Signaling Complexes to Suppress Host Defense

Toll-like receptors (TLRs) are crucial in the innate immune response to pathogens, in that they recognize and respond to pathogen associated molecular patterns, which leads to activation of intracellular signaling pathways and altered gene expression. Vaccinia virus (VV), the poxvirus used to vaccin...

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Detalles Bibliográficos
Autores principales: Harte, Mary T., Haga, Ismar R., Maloney, Geraldine, Gray, Pearl, Reading, Patrick C., Bartlett, Nathan W., Smith, Geoffrey L., Bowie, Andrew, O'Neill, Luke A.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193841/
https://www.ncbi.nlm.nih.gov/pubmed/12566418
http://dx.doi.org/10.1084/jem.20021652

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