The Major Histocompatibility Complex–related Fc Receptor for IgG (FcRn) Binds Albumin and Prolongs Its Lifespan

The inverse relationship between serum albumin concentration and its half-life suggested to early workers that albumin would be protected from a catabolic fate by a receptor-mediated mechanism much like that proposed for IgG. We show here that albumin binds FcRn in a pH dependent fashion, that the l...

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Detalles Bibliográficos
Autores principales: Chaudhury, Chaity, Mehnaz, Samina, Robinson, John M., Hayton, William L., Pearl, Dennis K., Roopenian, Derry C., Anderson, Clark L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193842/
https://www.ncbi.nlm.nih.gov/pubmed/12566415
http://dx.doi.org/10.1084/jem.20021829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193842/
https://www.ncbi.nlm.nih.gov/pubmed/12566415
http://dx.doi.org/10.1084/jem.20021829

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