Cargando…

Biallelic Germline Transcription at the κ Immunoglobulin Locus

Rearrangement of antigen receptor genes generates a vast array of antigen receptors on lymphocytes. The establishment of allelic exclusion in immunoglobulin genes requires differential treatment of the two sequence identical alleles. In the case of the κ immunoglobulin locus, changes in chromatin st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Nandita, Bergman, Yehudit, Cedar, Howard, Chess, Andrew
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193856/ https://www.ncbi.nlm.nih.gov/pubmed/12629064 http://dx.doi.org/10.1084/jem.20021392

Ejemplares similares

A Novel Pax5-Binding Regulatory Element in the Igκ Locus
por: Levin-Klein, Rena, et al.
Publicado: (2014)

Asynchronous Replication Timing: A Mechanism for Monoallelic Choice During Development
por: Bergman, Yehudit, et al.
Publicado: (2021)

Clonally stable Vκ allelic choice instructs Igκ repertoire
por: Levin-Klein, Rena, et al.
Publicado: (2017)

Biallelic germline nonsense variant of MLH3 underlies polyposis predisposition
por: Olkinuora, Alisa, et al.
Publicado: (2018)

P1408: MONOALLELIC AND BIALLELIC GERMLINE MUTATIONS AFFECTING THE TRANSCRIPTION FACTOR HELIOS CAUSE PLEIOTROPIC DEFECTS OF IMMUNITY
por: Mayr, D., et al.
Publicado: (2022)

Effect of downregulation of germline transcripts on immunoglobulin A isotype differentiation
Publicado: (1993)

Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome
por: Golubicki, Mariano, et al.
Publicado: (2020)

Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation
por: Thian, Marini, et al.
Publicado: (2020)

Identification of biallelic germline variants of SRP68 in a sporadic case with severe congenital neutropenia
por: Schmaltz-Panneau, Barbara, et al.
Publicado: (2021)

Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility
por: Villarroya-Beltri, Carolina, et al.
Publicado: (2022)

Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents
por: Olkinuora, Alisa Petriina, et al.
Publicado: (2022)

Biallelic BRCA Loss and Homologous Recombination Deficiency in Nonbreast/Ovarian Tumors in Germline BRCA1/2 Carriers
por: Wineland, Dylane, et al.
Publicado: (2023)

BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
por: Maxwell, Kara N., et al.
Publicado: (2017)

Chromosomal coordination and differential structure of asynchronous replicating regions
por: Blumenfeld, Britny, et al.
Publicado: (2021)

Muscle injury causes long-term changes in stem-cell DNA methylation
por: Falick Michaeli, Tal, et al.
Publicado: (2022)

Data on haplotype-supported immunoglobulin germline gene inference
por: Kirik, Ufuk, et al.
Publicado: (2017)

On the significance of germline cytogenetic rearrangements at MYCN locus in neuroblastoma
por: Lipska, Beata S, et al.
Publicado: (2013)

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
por: Epsztejn-Litman, Silvina, et al.
Publicado: (2008)

Immunoglobulin β Signaling Regulates Locus Accessibility for Ordered Immunoglobulin Gene Rearrangements
por: Maki, Kazushige, et al.
Publicado: (2000)

Structure of Germline Immunoglobulin Heavy-Chain γ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells
por: Xu, Minzhen, et al.
Publicado: (1990)

Immunoglobulin germline gene variation and its impact on human disease
por: Mikocziova, Ivana, et al.
Publicado: (2021)

Biallelic deleterious germline SH2B3 variants cause a novel syndrome of myeloproliferation and multi‐organ autoimmunity
por: Blombery, Piers, et al.
Publicado: (2023)

The 3′ end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four γ genes
por: Dunnick, Wesley A., et al.
Publicado: (2005)

Ketogenic diet attenuates cerebellar atrophy progression in a subject with a biallelic variant at the ATAD3A locus
por: Al Madhoun, Ashraf, et al.
Publicado: (2019)

A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance
por: Ku, Chia-Jui, et al.
Publicado: (2015)

Pre-B Cell Receptor Signaling Induces Immunoglobulin κ Locus Accessibility by Functional Redistribution of Enhancer-Mediated Chromatin Interactions
por: Stadhouders, Ralph, et al.
Publicado: (2014)

AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets
por: Lees, William D., et al.
Publicado: (2023)

High-sensitivity microsatellite instability assessment for the detection of mismatch repair defects in normal tissue of biallelic germline mismatch repair mutation carriers
por: González-Acosta, Maribel, et al.
Publicado: (2020)

Aberrant DNA Methylation in ES Cells
por: Ludwig, Guy, et al.
Publicado: (2014)

Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes
por: Mikocziova, Ivana, et al.
Publicado: (2021)

Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia‐like phenotype, and no chromosome fragility
por: Keupp, Katharina, et al.
Publicado: (2019)

A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus
por: Spisak, Sandor, et al.
Publicado: (2023)

NF-κB and the Immunoglobulin κ Gene Enhancer
por: Sen, Ranjan
Publicado: (2004)

Case Report: Heterozygous Germline Variant in EIF6 Additional to Biallelic SBDS Pathogenic Variants in a Patient With Ribosomopathy Shwachman–Diamond Syndrome
por: Taha, Ibrahim, et al.
Publicado: (2022)

Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms
por: Jäger, Roland, et al.
Publicado: (2014)

Ketogenic diet attenuates cerebellar atrophy progression in a subject with a biallelic variant at the ATAD3A locus [Response to Letter]
por: Al Madhoun, Ashraf, et al.
Publicado: (2019)

Multiple Sclerosis Is Associated with Immunoglobulin Germline Gene Variation of Transitional B Cells
por: Lomakin, Y. A., et al.
Publicado: (2022)

Unexpected Rearrangement and Expression of the Immunoglobulin λ1 Locus in Scid Mice
por: Ruetsch, Norman R., et al.
Publicado: (2000)

Immunoglobulin G Locus Events in Soft Tissue Sarcoma Cell Lines
por: Chen, Zhengshan, et al.
Publicado: (2011)

The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_g4c7a4d93ni3rr70hekn9luogr