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Interleukin 1 Receptor Dependence of Serum Transferred Arthritis Can be Circumvented by Toll-like Receptor 4 Signaling

Inflammatory arthritis is associated with the release of a network of key cytokines. In T cell receptor transgenic K/BxN mice interleukin (IL)-1 plays a key role in joint swelling and destruction, as suggested by the ability of anti–IL-1receptor (IL-1R) antibody treatment to delay the onset and slow...

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Detalles Bibliográficos
Autores principales: Choe, Jung-Yoon, Crain, Brian, Wu, Sarah R., Corr, Maripat
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193870/
https://www.ncbi.nlm.nih.gov/pubmed/12591910
http://dx.doi.org/10.1084/jem.20021850

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