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Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice

Natural killer (NK) cells protect hosts against viral pathogens and transformed cells. IL-15 is thought to play a critical role in NK cell development, but its role in the regulation of peripheral NK cells is less well defined. We now find that adoptive transfer of normal NK cells into mice lacking...

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Detalles Bibliográficos
Autores principales: Koka, Rima, Burkett, Patrick R., Chien, Marcia, Chai, Sophia, Chan, Faye, Lodolce, James P., Boone, David L., Ma, Averil
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193874/
https://www.ncbi.nlm.nih.gov/pubmed/12695489
http://dx.doi.org/10.1084/jem.20021836