Human Cytomegalovirus Glycoprotein UL16 Causes Intracellular Sequestration of NKG2D Ligands, Protecting Against Natural Killer Cell Cytotoxicity

The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I–related ligands, including the MIC and ULBP proteins. Infection, stress, or transformation can induce NKG2D ligand expression, result...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunn, Claire, Chalupny, N. Jan, Sutherland, Claire L., Dosch, Stephanie, Sivakumar, P.V., Johnson, David C., Cosman, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193902/
https://www.ncbi.nlm.nih.gov/pubmed/12782710
http://dx.doi.org/10.1084/jem.20022059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193902/
https://www.ncbi.nlm.nih.gov/pubmed/12782710
http://dx.doi.org/10.1084/jem.20022059

Ejemplares similares