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Protein Kinase C θ Affects Ca(2+) Mobilization and NFAT Activation in Primary Mouse T Cells

Protein kinase C (PKC)θ is an established component of the immunological synapse and has been implicated in the control of AP-1 and NF-κB. To study the physiological function of PKCθ, we used gene targeting to generate a PKCθ null allele in mice. Consistently, interleukin 2 production and T cell pro...

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Detalles Bibliográficos
Autores principales:	Pfeifhofer, Christa, Kofler, Kurt, Gruber, Thomas, Ghaffari Tabrizi, Nassim, Lutz, Christina, Maly, Karl, Leitges, Michael, Baier, Gottfried
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193906/ https://www.ncbi.nlm.nih.gov/pubmed/12782715 http://dx.doi.org/10.1084/jem.20020234

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