CD4(+)CD25(+) Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness

CD4(+)CD25(+) regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4(+)CD25(−)T cells and are potent suppressors of T cell activation in vitro. Their mechanism of suppression remains unknown, but most in vitro studies suggest that it is cell contact–dependent and cytokine indep...

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Detalles Bibliográficos
Autores principales: Piccirillo, Ciriaco A., Letterio, John J., Thornton, Angela M., McHugh, Rebecca S., Mamura, Mizuko, Mizuhara, Hidekazu, Shevach, Ethan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193919/
https://www.ncbi.nlm.nih.gov/pubmed/12119348
http://dx.doi.org/10.1084/jem.20020590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193919/
https://www.ncbi.nlm.nih.gov/pubmed/12119348
http://dx.doi.org/10.1084/jem.20020590

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