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CD4(+)CD25(+) Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness

CD4(+)CD25(+) regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4(+)CD25(−)T cells and are potent suppressors of T cell activation in vitro. Their mechanism of suppression remains unknown, but most in vitro studies suggest that it is cell contact–dependent and cytokine indep...

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Detalles Bibliográficos
Autores principales:	Piccirillo, Ciriaco A., Letterio, John J., Thornton, Angela M., McHugh, Rebecca S., Mamura, Mizuko, Mizuhara, Hidekazu, Shevach, Ethan M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193919/ https://www.ncbi.nlm.nih.gov/pubmed/12119348 http://dx.doi.org/10.1084/jem.20020590

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