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Infectious Tolerance: Human CD25(+) Regulatory T Cells Convey Suppressor Activity to Conventional CD4(+) T Helper Cells

Regulatory CD4(+)CD25(+) T cells (Treg) are mandatory for maintaining immunologic self-tolerance. We demonstrate that the cell-cell contact–mediated suppression of conventional CD4(+) T cells by human CD25(+) Treg cells is fixation resistant, independent from membrane-bound TGF-β but requires activa...

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Detalles Bibliográficos
Autores principales:	Jonuleit, Helmut, Schmitt, Edgar, Kakirman, Hacer, Stassen, Michael, Knop, Jürgen, Enk, Alexander H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193929/ https://www.ncbi.nlm.nih.gov/pubmed/12119350 http://dx.doi.org/10.1084/jem.20020394

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