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Pancreatic Lymph Nodes Are Required for Priming of β Cell Reactive T Cells in NOD Mice
Nonobese diabetic (NOD) mice develop spontaneous autoimmune diabetes that results from the destruction of insulin secreting β cells by diabetogenic T cells. The time and location of the encounter of autoantigen(s) by naive autoreactive T cells in normal NOD mice are still elusive. To address these i...
Autores principales: | Gagnerault, Marie-Claude, Luan, Jian Jian, Lotton, Chantal, Lepault, Françoise |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193939/ https://www.ncbi.nlm.nih.gov/pubmed/12163565 http://dx.doi.org/10.1084/jem.20011353 |
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