Cargando…

Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection

To elucidate the role of class switch recombination (CSR) and somatic hypermutation (SHM) in virus infection, we have investigated the influence of the primary and secondary infections of influenza virus on mice deficient of activation-induced cytidine deaminase (AID), which is absolutely required f...

Descripción completa

Detalles Bibliográficos
Autores principales: Harada, Yuichi, Muramatsu, Masamichi, Shibata, Toshikatsu, Honjo, Tasuku, Kuroda, Kazumichi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193959/
https://www.ncbi.nlm.nih.gov/pubmed/12796467
http://dx.doi.org/10.1084/jem.20021457

Ejemplares similares