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Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis
Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous system (CNS) that in many patients first presents clinically as optic neuritis. The relationship of optic neuritis to MS is not well understood. We have generated novel T cell receptor (TCR) transgenic mice spec...
Autores principales: | Bettelli, Estelle, Pagany, Maria, Weiner, Howard L., Linington, Christopher, Sobel, Raymond A., Kuchroo, Vijay K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193967/ https://www.ncbi.nlm.nih.gov/pubmed/12732654 http://dx.doi.org/10.1084/jem.20021603 |
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