Cross-linking the B7 Family Molecule B7-DC Directly Activates Immune Functions of Dendritic Cells

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B7-DC molecules are known to function as ligands on antigen-presenting cells (APCs), enhancing T cell activation. In this study, cross-linking B7-DC with the monoclonal antibody sHIgM12 directly potentiates dendritic cell (DC) function by enhancing DC presentation of major histocompatibility complex...

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Detalles Bibliográficos
Autores principales: Nguyen, Loc T., Radhakrishnan, Suresh, Ciric, Bogoljub, Tamada, Koji, Shin, Tahiro, Pardoll, Drew M., Chen, Lieping, Rodriguez, Moses, Pease, Larry R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193990/
https://www.ncbi.nlm.nih.gov/pubmed/12438431
http://dx.doi.org/10.1084/jem.20021466
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