Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4(+) T Cell Responses Against MAGE-6 in HLA-DRB10401(+) Patients With Renal Cell Carcinoma or Melanoma

T helper type 1 (Th1)-type CD4(+) antitumor T cell help appears critical to the induction and maintenance of antitumor cytotoxic T lymphocyte (CTL) responses in vivo. In contrast, Th2- or Th3/Tr-type CD4(+) T cell responses may subvert Th1-type cell-mediated immunity, providing a microenvironment co...

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Detalles Bibliográficos
Autores principales: Tatsumi, Tomohide, Kierstead, Lisa S., Ranieri, Elena, Gesualdo, Loreto, Schena, Francesco P., Finke, James H., Bukowski, Ronald M., Mueller-Berghaus, Jan, Kirkwood, John M., Kwok, William W., Storkus, Walter J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193999/
https://www.ncbi.nlm.nih.gov/pubmed/12208877
http://dx.doi.org/10.1084/jem.20012142

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