Cargando…

Induction of NFATc2 Expression by Interleukin 6 Promotes T Helper Type 2 Differentiation

Interleukin (IL)-6 is produced by professional antigen-presenting cells (APCs) such as B cells, macrophages, and dendritic cells. It has been previously shown that APC-derived IL-6 promotes the differentiation of naive CD4(+) T cells into effector T helper type 2 (Th2) cells. Here, we have studied t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diehl, Sean, Chow, Chi-Wing, Weiss, Linda, Palmetshofer, Alois, Twardzik, Thomas, Rounds, Laura, Serfling, Edgar, Davis, Roger J., Anguita, Juan, Rincón, Mercedes
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194007/ https://www.ncbi.nlm.nih.gov/pubmed/12093869 http://dx.doi.org/10.1084/jem.20020026

Ejemplares similares

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4(+) T lymphocytes by CD4(+) CD25(+) regulatory T cells
por: Bopp, Tobias, et al.
Publicado: (2005)

The Interleukin 2 Receptor α Chain/CD25 Promoter Is a Target for Nuclear Factor of Activated T Cells
por: Schuh, Kai, et al.
Publicado: (1998)

NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation
por: Giampaolo, Sabrina, et al.
Publicado: (2023)

Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation
por: Muhammad, Khalid, et al.
Publicado: (2018)

B cell development is critically dependent on NFATc1 activity
por: Giampaolo, Sabrina, et al.
Publicado: (2018)

Architecture and Expression of the Nfatc1 Gene in Lymphocytes
por: Rudolf, Ronald, et al.
Publicado: (2014)

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes
por: Serfling, Edgar, et al.
Publicado: (2012)

NFATc1 Regulation of TRAIL Expression in Human Intestinal Cells
por: Wang, Qingding, et al.
Publicado: (2011)

Hematopoietic Stem and Progenitor Cell Maintenance and Multiple Lineage Differentiation Is an Integral Function of NFATc1
por: Barahona de Brito, Carlotta, et al.
Publicado: (2022)

NFATC1 and NFATC2 expression patterns in human osteochondromas
por: Wang, Yuanyuan, et al.
Publicado: (2023)

Calcineurin-independent NFATc1 signaling is essential for survival of Burkitt lymphoma cells
por: Murti, Krisna, et al.
Publicado: (2023)

Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity
por: Xiao, Yin, et al.
Publicado: (2020)

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
por: Asagiri, Masataka, et al.
Publicado: (2005)

SUMOylation of the transcription factor NFATc1 leads to its subnuclear relocalization and IL2 repression by HDAC
por: Nayak, A, et al.
Publicado: (2009)

The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts
por: Baur, Johannes, et al.
Publicado: (2018)

CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4
Publicado: (1993)

NFATc1 controls the cytotoxicity of CD8(+) T cells
por: Klein-Hessling, Stefan, et al.
Publicado: (2017)

Priming for T helper type 2 differentiation by interleukin 2-mediated induction of IL-4 receptor α chain expression
por: Liao, Wei, et al.
Publicado: (2008)

Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells
por: Giampaolo, Sabrina, et al.
Publicado: (2017)

Induction of Interleukin-10 Producing Dendritic Cells As a Tool to Suppress Allergen-Specific T Helper 2 Responses
por: Schülke, Stefan
Publicado: (2018)

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
por: Xiao, Zhi-Jie, et al.
Publicado: (2017)

The inducible transcription factor NFATc1 controls the survival of germinal center B lymphocytes
por: Serfling, E, et al.
Publicado: (2009)

Interleukin (IL)-6 Directs the Differentiation of IL-4–producing CD4(+) T Cells
por: Rincón, Mercedes, et al.
Publicado: (1997)

Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma
por: Jakobi, Marielena, et al.
Publicado: (2020)

Interferon Regulatory Factor 4 (IRF4) Interacts with NFATc2 to Modulate Interleukin 4 Gene Expression
por: Rengarajan, Jyothi, et al.
Publicado: (2002)

NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells
por: Alrefai, Hani, et al.
Publicado: (2016)

EWSR1-NFATC2 and FUS-NFATC2 Gene Fusion-Associated Mesenchymal Tumors: Clinicopathologic Correlation and Literature Review
por: Bode-Lesniewska, Beata, et al.
Publicado: (2019)

Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production
por: Cohn, Lauren, et al.
Publicado: (1997)

Corrigendum: NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells
por: Alrefai, Hani, et al.
Publicado: (2016)

Helper cells in the autologous mixed lymphocyte reaction. III. Production of helper factor(s) distinct from interleukin 2
Publicado: (1982)

A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development
por: Klein-Hessling, Stefan, et al.
Publicado: (2016)

Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
por: Kuzumi, Ai, et al.
Publicado: (2021)

Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression
por: Bopp, Tobias, et al.
Publicado: (2007)

Type I interferon is required for T helper (Th) 2 induction by dendritic cells
por: Webb, Lauren M, et al.
Publicado: (2017)

Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation
por: Perotti, V., et al.
Publicado: (2019)

Interleukin-12 is not essential for silicosis in mice
por: Davis, Gerald S, et al.
Publicado: (2006)

MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata
por: Qi, Si-si, et al.
Publicado: (2023)

BDNF activates an NFI-dependent neurodevelopmental timing program by sequestering NFATc4
por: Ding, Baojin, et al.
Publicado: (2018)

Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1
por: Nakamura, Shinya, et al.
Publicado: (2017)

Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus
por: Evans, Kathryn E, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_uc7c9plni59h6o8lbojn0dfjc7